Complete all gigs and NCPD Scanner Hustles in City Center.

Install at least one implant in each system and body part.

Kill or incapacitate an enemy who threw a grenade at you.

Find all the tarot graffiti for the job Fool on the Hill.

Buy all vehicles available for purchase.

Find all fast travel dataterms.

Kill or incapacitate 3 enemies in quick succession with a revolver or pistol in close combat.

Shoot an enemy grenade in midair with a revolver.

Craft 3 Legendary items.

Complete all Cyberpsycho Sightings.

Complete all gigs and NCPD Scanner Hustles in Heywood.

Complete all gigs and NCPD Scanner Hustles in Westbrook.

Complete a Breach Protocol with a minimum of 3 daemons uploaded.

Kill or incapacitate 50 enemies while time is slowed.

Perform the Distract Enemies quickhack 30 times without drawing attention to yourself.

Collect all items that once belonged to Johnny Silverhand.

Complete all gigs and NCPD Scanner Hustles in the Badlands.

Kill or incapacitate 3 enemies with one "Detonate Grenade" quickhack.

Use a dialogue option related to V's life path 10 times.

Reach the max level in any skill.

While Berserk cyberware is active, perform a Superhero Landing to kill or incapacitate 2 enemies.

Complete the main storyline.

Complete all gigs and NCPD Scanner Hustles in Pacifica.

Complete all gigs and NCPD Scanner Hustles in Santo Domingo.

Kill or incapacitate 300 enemies using ranged weapons.

Kill or incapacitate 100 enemies using melee weapons.

Kill or incapacitate 2 enemies with the same sniper rifle shot.

After reviving with Second Heart, kill or incapacitate the enemy who killed you within 5 seconds.

Complete all gigs and NCPD Scanner Hustles in Watson.

Reach max Street Cred.

Save President Myers.

Complete every Gig in Dogtown.

Become Dogtown's most wanted criminal.

Steal the Arasaka medical truck or deliver 10 vehicles to El Capitan.

Eliminate three bosses from the "Increased criminal activity" category.

Complete “Run This Town”.

Unlock all Perks in the Relic Perk tree.

Defeat the Chimera.

Complete "Leave In Silence".

Complete "Leave In Silence".

Complete "The Killing Moon".

Complete "The Killing Moon".

Complete "Things Done Changed".