Activate every Robo-Janitor prototype in Chasm 24

Have at least one of each type of ambulance fully upgraded in the same hospital.

Win every award in a single hospital

Send 100 cured patients through the Yesterizer in Clockwise-above-Thyme

Capture 100 Ghosts

Collect 20 patients in one trip with a Pantomobile.

Run 50 Marketing Campaigns

Earn 1 Star at each hospital in Culture Shock

Earn 1 Star at each hospital in A Stitch In Time

Earn 1 Star at each hospital in Speedy Recovery

Earn 1 Star at each hospital in the Pointy Mountains

Earn 1 Star at each hospital on Pebberley Island

Earn 1 Star at each hospital in Close Encounters

Earn 1 Star at each hospital in Off The Grid

Complete 50 Research Projects

Complete Superbug Project "Hair Removal"

Complete Superbug Project "Learning Machine Learning"

Complete 50 Research Nodes

Cure a patient with Frogborne

Cure 1 Patient

Cure 1000 Patients

Expose 50 Alien Infiltrators

Complete Wave 42 on Topless Mountain

Achieve a high VIBE rating at Fitzpocket Academy

Maximise your Green Energy capacity in Windsock

Cure a patient in the Herb Garden

Have a Level 10 Hospital

Have a Level 20 Hospital

Receive the highest possible Eco Rating

Complete a Multiplayer Challenge

Reach $50,000,000 Organisation Value

Complete R.E.M.I. X versions of Hogsport, Lower Bullocks & Flottering

Complete R.E.M.I. X versions of Mitton University, Tumble & Flemington

Complete Wave 18 at Mudbury Festival

Earn 10,000 Kudosh

Earn 15 Gold Stars

Earn 108 Gold Stars

Earn 30 Gold Stars

Earn 45 Gold Stars

Earn 54 Gold Stars

Earn 63 Gold Stars

Earn 72 Gold Stars

Earn 81 Gold Stars

Earn 90 Gold Stars

Earn 99 Gold Stars

Cure 100 patients from time portals in a single year

Cure a patient with Lightheadedness, Beheadedness, Hotheadedness, and Byteheadedness in Clockwise-above-Thyme

Reach the top of every league table at once for 3 months

Train a World-Class Psychiatrist

Train a World-Class Researcher

Train Roderick Cushion to Level 5 at Plywood Studios

Train a World-Class Surgeon

Unlock every plot in Overgrowth

Conduct 25 Machine Upgrades

Get a Curing Spree on Topless Mountain

Injure someone with an exploding machine

Have a Level 5 De-lux Clinic at the Underlook Hotel

Shoot 1 Monobeast

Shoot 10 Monobeasts in a row without missing

Complete the "Cheesier Gubbins" Research Project in Swelbard

Knock the socks off of Bartholomew F. Yeti